Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 100528032
Gene Symbol: KLRC4-KLRK1
KLRC4-KLRK1
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.050 Biomarker BEFREE Chitosan nanoparticle-based delivery of fused NKG2D-IL-21 gene suppresses colon cancer growth in mice. 28450784

2017
Entrez Id: 100528032
Gene Symbol: KLRC4-KLRK1
KLRC4-KLRK1
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.050 AlteredExpression BEFREE Entinostat enhances NK cell killing of cancer cells through upregulation of both NKG2D and its ligands, suggesting an attractive approach for augmenting NK cell immunotherapy of solid tumors such as colon carcinoma and sarcomas. 24203492

2015
Entrez Id: 100528032
Gene Symbol: KLRC4-KLRK1
KLRC4-KLRK1
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.050 Biomarker BEFREE In this study, we explored the potential therapeutic utility of the NKG2D ligand ULBP2 for the treatment of colon carcinoma. 24242212

2014
Entrez Id: 100528032
Gene Symbol: KLRC4-KLRK1
KLRC4-KLRK1
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.050 Biomarker BEFREE Treatment with a fusion protein of the extracellular domains of NKG2D to IL-15 retards colon cancer growth in mice. 24810637

2014
Entrez Id: 100528032
Gene Symbol: KLRC4-KLRK1
KLRC4-KLRK1
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.050 AlteredExpression BEFREE Tumor metastasis and lack of NKG2D ligand (NKG2DL) expression are associated with poor prognosis in patients with colon cancer. 24190430

2013