Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.320 Biomarker CTD_human MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastoma. 20131314

2010
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.320 Biomarker BEFREE Berger, Lack of the DNA repair protein O(6)-methylguanine-DNA methyltransferase in histologically normal brain adjacent to primary brain tumors, Proc.Natl.Acad.Sci.U.S.A. 93 (1996) 6941-6946]. 17500046

2007
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.320 GeneticVariation BEFREE The frequencies of MGMT genotypes in examined primary brain tumors were not different from normal subjects. 14669534

2003
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.310 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.310 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.310 GeneticVariation BEFREE The frequency of CC genotype for CDKN2 p16 540 C>G was significantly two-fold higher (p<0.001) and possessing a C allele conferred a ~7-fold increased risk (p=0.005) of primary brain tumor. 26124340

2015
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.310 GeneticVariation BEFREE Cyclin D1 gene G870A variants and primary brain tumors. 23991960

2013
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.310 Biomarker CTD_human Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats. 20932960

2011
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.310 Biomarker BEFREE We undertook this study to understand how the transcription factor Sox2 contributes to the malignant phenotype of glioblastoma multiforme (GBM), the most aggressive primary brain tumor. 22069467

2011
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.310 Biomarker CTD_human Evaluation of genetic alterations in cancer-related genes in lung and brain tumors from B6C3F1 mice exposed to 1,3-butadiene or chloroprene. 16860786

2007
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.310 Biomarker CTD_human [p16 protein expression in the transplacental induced brain tumor in rat]. 15144691

2004
Entrez Id: 6285
Gene Symbol: S100B
S100B
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 10788
Gene Symbol: IQGAP2
IQGAP2
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 24147
Gene Symbol: FJX1
FJX1
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 154796
Gene Symbol: AMOT
AMOT
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 3689
Gene Symbol: ITGB2
ITGB2
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 8826
Gene Symbol: IQGAP1
IQGAP1
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 27436
Gene Symbol: EML4
EML4
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human Isolated central nervous system progression on Crizotinib: an Achilles heel of non-small cell lung cancer with EML4-ALK translocation? 22986231

2012
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human Resveratrol Targeting of Carcinogen-Induced Brain Endothelial Cell Inflammation Biomarkers MMP-9 and COX-2 is Sirt1-Independent. 22523472

2012
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human Isolated central nervous system progression on Crizotinib: an Achilles heel of non-small cell lung cancer with EML4-ALK translocation? 22986231

2012
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats. 20932960

2011
Entrez Id: 5970
Gene Symbol: RELA
RELA
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats. 20932960

2011