Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal
0.310 Biomarker BEFREE Intrathecal injection of either the CSF-1 blocker or IL-1 inhibitor attenuated thermal hyperalgesia in MRL/lpr mice. 28072466

2017

Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal
0.310 Therapeutic CTD_human Interleukin-1 receptor antagonist ameliorates neonatal lipopolysaccharide-induced long-lasting hyperalgesia in the adult rats. 20937348

2011

Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal
0.310 Biomarker CTD_human Interleukin-1 receptor antagonist ameliorates neonatal lipopolysaccharide-induced long-lasting hyperalgesia in the adult rats. 20937348

2011

Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal
0.310 Therapeutic CTD_human Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. 17174526

2007

Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal
0.310 Biomarker CTD_human Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. 17174526

2007

Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal
0.310 Therapeutic CTD_human A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine. 15317861

2004

Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal
0.310 Biomarker CTD_human A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine. 15317861

2004

Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal
0.310 Biomarker CTD_human Substance P and capsaicin-induced mechanical hyperalgesia in the rat knee joint; the involvement of bradykinin B1 and B2 receptors. 8864563

1996

Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal
0.310 Therapeutic CTD_human Substance P and capsaicin-induced mechanical hyperalgesia in the rat knee joint; the involvement of bradykinin B1 and B2 receptors. 8864563

1996