Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0878500
Disease: Intraepithelial Neoplasia
Intraepithelial Neoplasia 		0.350 AlteredExpression BEFREE Heparanase and cyclooxygenase-2 gene and protein expressions during progression of oral epithelial dysplasia to carcinoma. 22575501

2012
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0878500
Disease: Intraepithelial Neoplasia
Intraepithelial Neoplasia 		0.350 Biomarker BEFREE COX-2 and, especially, EP2 were increased in the Barrett's metaplasia-intraepithelial neoplasia-adenocarcinoma sequence. 19843025

2010
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0878500
Disease: Intraepithelial Neoplasia
Intraepithelial Neoplasia 		0.350 Biomarker BEFREE Cox-2 was detected in the epithelium of all OLP specimens investigated, as well as in epithelial dysplasias and OSCC. 17530268

2007
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0878500
Disease: Intraepithelial Neoplasia
Intraepithelial Neoplasia 		0.350 AlteredExpression BEFREE Expression of both bcl-2 and cox-2 were increased in non-dysplastic Barrett's (p = 0.0077, p = 0.0037), intraepithelial neoplasia (p = 0.0053, p = 0.0220) and adenocarcinoma (p < 0.0001, p < 0.0001) compared to squamous epithelium or reflux-esophagitis. 16550596

2006
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0878500
Disease: Intraepithelial Neoplasia
Intraepithelial Neoplasia 		0.350 AlteredExpression BEFREE To elucidate the role of cox-2 in esophageal carcinogenesis, we evaluated the expression of cox-2 in normal squamous epithelium squamous epithelial dysplasia (n=47), and squamous cell carcinoma of the esophagus (n=86) by immunohistochemistry, reverse transcription-PCR assay, and western blotting. 12957358

2003
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0878500
Disease: Intraepithelial Neoplasia
Intraepithelial Neoplasia 		0.350 Biomarker CTD_human Cyclooxygenase-2 expression is up-regulated in transitional cell carcinoma and its preneoplastic lesions in the human urinary bladder. 10873095

2000
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0878500
Disease: Intraepithelial Neoplasia
Intraepithelial Neoplasia 		0.350 Biomarker CTD_human Expression of cyclooxygenase-2 (COX-2) in human invasive transitional cell carcinoma (TCC) of the urinary bladder. 10582676

1999