Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.040 GeneticVariation BEFREE COX-1(rs1330344, rs3842788) and COX-2 rs689466 interacted in SVO, but had no additive effect with ischemic stroke and other subtypes. 31735164

2019

Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.040 GeneticVariation BEFREE This study aimed to explore the association between GPIa, COX-2 gene polymorphisms and aspirin resistance in the ischemic stroke patients from the southern part of Jiangsu province. 28948649

2018

Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.040 AlteredExpression BEFREE Whereas the role of COX-1 expressed in platelets in acute coronary syndromes and ischemic stroke is definitely established through several large clinical studies with aspirin, the role of COX-2 activity in these settings is still unclear, because this enzyme was characterized only recently (1991) and its inhibitors (coxibs) only became available in 1998. 19485927

2010

Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.040 Biomarker BEFREE Consequently, inhibition of iNOS and COX-2 could be a valuable addition to treatment strategies for ischemic stroke. 9616775

1997