Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5644
Gene Symbol: PRSS1
PRSS1
CUI: C1279945
Disease: Acute interstitial pneumonia
Acute interstitial pneumonia 		0.040 GeneticVariation BEFREE Recently, we have demonstrated that PRSS1 mutations cause ectopic trypsinogen activation and thereby result in type 1 autoimmune pancreatitis (AIP). 28151472

2017
Entrez Id: 5644
Gene Symbol: PRSS1
PRSS1
CUI: C1279945
Disease: Acute interstitial pneumonia
Acute interstitial pneumonia 		0.040 GeneticVariation BEFREE PRSS1: IVS 2 +56_60 del CCCAG is a noval mutant which may contribute to AIP pathogenesis. 24236450

2014
Entrez Id: 5644
Gene Symbol: PRSS1
PRSS1
CUI: C1279945
Disease: Acute interstitial pneumonia
Acute interstitial pneumonia 		0.040 GeneticVariation BEFREE Patients with PRSS1 variants had an increased risk of AIP with odds ratio 22.37 (95% confidence interval: 2.96-168.8, P = 0.003) and higher frequency of serum IgG4 above 280 mg/dL. 24909264

2014
Entrez Id: 5644
Gene Symbol: PRSS1
PRSS1
CUI: C1279945
Disease: Acute interstitial pneumonia
Acute interstitial pneumonia 		0.040 GeneticVariation BEFREE Two novel mutations (p.81Leu→Met and p.91Ala→Ala) were found in PRSS1 gene from four patients with AIP. 23745036

2013