DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Adenocarcinoma of large intestine ×

Gene: PIK3CA ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	5290
Gene Symbol:	PIK3CA

PIK3CA

CUI:	C1319315
Disease:	Adenocarcinoma of large intestine

Adenocarcinoma of large intestine

0.320

Biomarker

BEFREE

GLI1 promotes cancer stemness through intracellular signaling pathway PI3K/Akt/NFκB in colorectal adenocarcinoma.

30321514

2018

Entrez Id:	5290
Gene Symbol:	PIK3CA

PIK3CA

CUI:	C1319315
Disease:	Adenocarcinoma of large intestine

Adenocarcinoma of large intestine

0.320

Biomarker

BEFREE

The phosphoinositide 3 kinase (PI3K)/Akt/mammalian target of the rapamycin (mTOR) pathway plays a significant role in colorectal adenocarcinoma.

27176231

2016

Entrez Id:	5290
Gene Symbol:	PIK3CA

PIK3CA

CUI:	C1319315
Disease:	Adenocarcinoma of large intestine

Adenocarcinoma of large intestine

0.320

CausalMutation

CGI