Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4953
Gene Symbol: ODC1
ODC1
CUI: C1332206
Disease: Adult Lymphoma
Adult Lymphoma
0.020 GeneticVariation BEFREE Indeed, sustained treatment with the Odc suicide inhibitor alpha-difluoromethylornithine (DFMO) or Odc heterozygosity markedly impairs lymphoma development in Emicro-Myc transgenic mice, and these effects are linked to the induction of the cyclin-dependent kinase (Cdk) inhibitor p27(Kip1), which is normally repressed by Myc. 19147568

2009

Entrez Id: 4953
Gene Symbol: ODC1
ODC1
CUI: C1332206
Disease: Adult Lymphoma
Adult Lymphoma
0.020 Biomarker BEFREE The Paju karyotype did not contain double minute chromosomes or any large homogeneously staining region such as that seen in a mouse lymphoma cell mutant that is resistant to difluoromethylornithine and overproduces ornithine decarboxylase (McConlogue, L., and Coffino, P. (1983) J. Biol.Chem.258, 12083-12086). 6436232

1984