Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia 		0.060 Biomarker BEFREE In this study, we examine the ability of leukemia microvesicles to induce proliferation in hematopoietic stem progenitor cells (HSPCs) via microRNA-21 dysregulation. 31429853

2020
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia 		0.060 AlteredExpression BEFREE We have shown that antagomiR inhibition of miRNA miR-21 and miR-196b activity is sufficient to ablate MLL-AF9 leukemia stem cells (LSC) in vivo. 29997117

2018
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia 		0.060 Biomarker BEFREE miRNA-21 regulates arsenic-induced anti-leukemia activity in myelogenous cell lines. 20143188

2011
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia 		0.060 Biomarker BEFREE The microRNA-21 (miR-21) has been identified as the only miRNA overexpressed in a variety of cancers, including leukemia. 20141427

2010
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia 		0.060 Biomarker BEFREE Therefore, exploiting synergistic effects between AMO-miR-21 and Ara-C might be an effective clinical strategy for leukemia chemotherapy. 20670480

2010
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia 		0.060 Biomarker BEFREE Collectively, these results provide important new insight into the pathogenesis of NK-cell lymphoma/leukemia and suggest targeting miR-21 and/or miR-155 may represent a useful approach to treating NK-cell lymphoma/leukemia. 19641183

2009