Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 Biomarker CTD_human Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization. 21501481

2011
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 Biomarker CTD_human Thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase mRNA and protein expression levels in solid tumors in large scale population analysis. 19020767

2008
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 GeneticVariation LHGDN Functional polymorphism of thymidylate synthase, but not of the COMT and IL-1B genes, is associated with breast cancer. 17385677

2007
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 GeneticVariation LHGDN Polymorphisms of one-carbon-metabolizing genes and risk of breast cancer in a population-based study. 17372271

2007
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 Biomarker CTD_human Polymorphisms in thymidylate synthase gene and susceptibility to breast cancer in a Chinese population: a case-control analysis. 16723031

2006
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 AlteredExpression LHGDN Difference in Ki67 and thymidylate synthase expression in primary tumour compared with metastatic nodes in breast cancer patients. 17065089

2006
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 AlteredExpression LHGDN The prognostic significance of thymidine phosphorylase, thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expressions in breast carcinomas. 14702180

2004
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 GeneticVariation LHGDN Methylenetetrahydrofolate reductase and thymidylate synthase polymorphisms are not associated with breast cancer risk or phenotype. 15510613

2004
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 Biomarker BEFREE Therefore, a semiquantitative polymerase chain reaction (PCR) technique to measure TS RNA concentration in breast tumour cell lines has been developed with potential for measuring TS RNA levels in individual breast tumours. 8028610

1994