Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 CausalMutation CLINVAR K-RasV14I recapitulates Noonan syndrome in mice. 25359213

2014
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 CausalMutation CLINVAR Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations. 24803665

2014
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 Biomarker MGD K-RasV14I recapitulates Noonan syndrome in mice. 25359213

2014
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 Biomarker GENOMICS_ENGLAND The RASopathies. 23875798

2013
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 CausalMutation CLINVAR Noonan syndrome: comparing mutation-positive with mutation-negative dutch patients. 23885229

2013
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 Biomarker GENOMICS_ENGLAND KRAS gene mutations in Noonan syndrome familial cases cluster in the vicinity of the switch II region of the G-domain: report of another family with metopic craniosynostosis. 22488932

2012
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 CausalMutation CLINVAR Spectrum of mutations in Noonan syndrome and their correlation with phenotypes. 21784453

2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 CausalMutation CLINVAR KRAS mutation detection in paired frozen and Formalin-Fixed Paraffin-Embedded (FFPE) colorectal cancer tissues. 21686179

2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 Biomarker GENOMICS_ENGLAND Noonan syndrome and clinically related disorders. 21396583

2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 CausalMutation CLINVAR Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders. 20949621

2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 GeneticVariation UNIPROT Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders. 20949621

2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 Biomarker GENOMICS_ENGLAND Craniosynostosis in patients with Noonan syndrome caused by germline KRAS mutations. 19396835

2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 GeneticVariation UNIPROT Craniosynostosis in patients with Noonan syndrome caused by germline KRAS mutations. 19396835

2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 Biomarker GENOMICS_ENGLAND Further evidence of genetic heterogeneity in Costello syndrome: involvement of the KRAS gene. 17468812

2007
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 CausalMutation CLINVAR Expansion of the genotypic and phenotypic spectrum in patients with KRAS germline mutations. 17056636

2007
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 GeneticVariation UNIPROT Further evidence of genetic heterogeneity in Costello syndrome: involvement of the KRAS gene. 17468812

2007
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 GeneticVariation UNIPROT Expansion of the genotypic and phenotypic spectrum in patients with KRAS germline mutations. 17056636

2007
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 CausalMutation CLINVAR Noonan syndrome and related disorders: dysregulated RAS-mitogen activated protein kinase signal transduction. 16987887

2006
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 GeneticVariation UNIPROT Germline KRAS mutations cause Noonan syndrome. 16474405

2006
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 GeneticVariation UNIPROT Germline missense mutations affecting KRAS Isoform B are associated with a severe Noonan syndrome phenotype. 16773572

2006
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 CausalMutation CLINVAR Germline KRAS mutations cause Noonan syndrome. 16474405

2006
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 Biomarker CTD_human

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 Biomarker GENOMICS_ENGLAND

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1860991
Disease: NOONAN SYNDROME 3
NOONAN SYNDROME 3 		0.900 GeneticVariation CLINVAR