Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 105804841
Gene Symbol: ZRS
ZRS
CUI: C1861355
Disease: Syndactyly, Type IV
Syndactyly, Type IV 		0.030 Biomarker BEFREE It had been identified that point mutation or genomic duplications of the long-range limb-specific cis-regulator - zone of polarizing activity regulatory sequence (ZRS) cause PPD or other limb deformities such as syndactyly type IV (SD4) and Triphalangeal thumb-polysyndactyly syndrome (TPTPS). 27922091

2016
Entrez Id: 105804841
Gene Symbol: ZRS
ZRS
CUI: C1861355
Disease: Syndactyly, Type IV
Syndactyly, Type IV 		0.030 Biomarker BEFREE Microduplications encompassing the Sonic hedgehog limb enhancer ZRS are associated with Haas-type polysyndactyly and Laurin-Sandrow syndrome. 24456159

2014
Entrez Id: 105804841
Gene Symbol: ZRS
ZRS
CUI: C1861355
Disease: Syndactyly, Type IV
Syndactyly, Type IV 		0.030 GeneticVariation BEFREE Both TPTPS and SD4 are due to duplications involving ZRS, the limb specific SHH enhancer. 18417549

2008