Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.600 Biomarker CLINGEN Targeted expression of mutated ALK induces neuroblastoma in transgenic mice. 22764207

2012
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.600 Biomarker CLINGEN ALK germline mutations in patients with neuroblastoma: a rare and weakly penetrant syndrome. 22071890

2012
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.600 GeneticVariation UNIPROT The constitutive activity of the ALK mutated at positions F1174 or R1275 impairs receptor trafficking. 21242967

2011
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.600 Biomarker CLINGEN Germline gain-of-function mutations of ALK disrupt central nervous system development. 21972109

2011
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.600 Biomarker CLINGEN Identification of ALK as a major familial neuroblastoma predisposition gene. 18724359

2008
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.600 Biomarker CLINGEN Oncogenic mutations of ALK kinase in neuroblastoma. 18923524

2008
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.600 GeneticVariation UNIPROT Activating mutations in ALK provide a therapeutic target in neuroblastoma. 18923525

2008
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.600 Biomarker CLINGEN Activating mutations in ALK provide a therapeutic target in neuroblastoma. 18923525

2008
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.600 GeneticVariation UNIPROT Identification of ALK as a major familial neuroblastoma predisposition gene. 18724359

2008
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.600 GeneticVariation UNIPROT Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. 18923523

2008
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.600 GeneticVariation CLINVAR

Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.600 CausalMutation CLINVAR

Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		0.600 SusceptibilityMutation CLINVAR