DisGeNET - a database of gene-disease associations

Source: ALL

Disease: PANCREATIC CANCER, SUSCEPTIBILITY TO, 3 ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	79728
Gene Symbol:	PALB2

PALB2

CUI:	C3150547
Disease:	PANCREATIC CANCER, SUSCEPTIBILITY TO, 3

PANCREATIC CANCER, SUSCEPTIBILITY TO, 3

0.400

Biomarker

GENOMICS_ENGLAND

Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer.

17200671

2007

Entrez Id:	79728
Gene Symbol:	PALB2

PALB2

CUI:	C3150547
Disease:	PANCREATIC CANCER, SUSCEPTIBILITY TO, 3

PANCREATIC CANCER, SUSCEPTIBILITY TO, 3

0.400

Biomarker

GENOMICS_ENGLAND

Fanconi anemia is associated with a defect in the BRCA2 partner PALB2.

17200672

2007

Entrez Id:	79728
Gene Symbol:	PALB2

PALB2

CUI:	C3150547
Disease:	PANCREATIC CANCER, SUSCEPTIBILITY TO, 3

PANCREATIC CANCER, SUSCEPTIBILITY TO, 3

0.400

CausalMutation

CLINVAR

Entrez Id:	79728
Gene Symbol:	PALB2

PALB2

CUI:	C3150547
Disease:	PANCREATIC CANCER, SUSCEPTIBILITY TO, 3

PANCREATIC CANCER, SUSCEPTIBILITY TO, 3

0.400

Biomarker

GENOMICS_ENGLAND

Entrez Id:	79728
Gene Symbol:	PALB2

PALB2

CUI:	C3150547
Disease:	PANCREATIC CANCER, SUSCEPTIBILITY TO, 3

PANCREATIC CANCER, SUSCEPTIBILITY TO, 3

0.400

Biomarker

GENOMICS_ENGLAND

Entrez Id:	79728
Gene Symbol:	PALB2

PALB2

CUI:	C3150547
Disease:	PANCREATIC CANCER, SUSCEPTIBILITY TO, 3

PANCREATIC CANCER, SUSCEPTIBILITY TO, 3

0.400

SusceptibilityMutation

CLINVAR