Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.030 Biomarker BEFREE The results confirm that COX-2/ PGE2 pathway is involved in immunosuppression induced by MDV-lymphoma cells. 29267390

2017
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.030 Biomarker BEFREE This work indicates that LMP1-mediated glycolysis regulates IL-1β, IL-6 and GM-CSF production through the NLRP3 inflammasome, COX-2 and P-p65 signaling pathways to enhance tumor-associated MDSC expansion, which leads to tumor immunosuppression in NPC. 28732079

2017
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.030 AlteredExpression BEFREE We have previously shown that genetic inhibition of tumor COX-2 expression reverses the immunosuppression induced by non-small cell lung cancer (NSCLC). 11320076

2001