Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 27034
Gene Symbol: ACAD8
ACAD8
Malignant neoplasm of colon and/or rectum
0.080 Biomarker BEFREE The decreasing rates of colorectal cancer suggest improved management and care in IBD. 30874294

2019

Entrez Id: 27034
Gene Symbol: ACAD8
ACAD8
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE Rates and characteristics of postcolonoscopy colorectal cancer in the Swedish IBD population: what are the differences from a non-IBD population? 30554159

2019

Entrez Id: 27034
Gene Symbol: ACAD8
ACAD8
Malignant neoplasm of colon and/or rectum
0.080 Biomarker BEFREE Patients with inflammatory bowel disease [IBD] colitis are at increased risk for colorectal cancer [CRC]. 29648663

2018

Entrez Id: 27034
Gene Symbol: ACAD8
ACAD8
Malignant neoplasm of colon and/or rectum
0.080 GeneticVariation BEFREE Compared with the general population, patients with inflammatory bowel disease [IBD] have an increased risk of developing colorectal cancer. 30202940

2018

Entrez Id: 27034
Gene Symbol: ACAD8
ACAD8
Malignant neoplasm of colon and/or rectum
0.080 Biomarker BEFREE Intestinal microbiota play a critical role in the maintenance of the host intestinal barrier homeostasis, while dysbiosis, which involves reduction in the microbiome diversity, can lead to progression of inflammatory disorders, such as IBD and colorectal cancer. 28337900

2017

Entrez Id: 27034
Gene Symbol: ACAD8
ACAD8
Malignant neoplasm of colon and/or rectum
0.080 Biomarker BEFREE Clonal evolution of colorectal cancer in IBD. 28174420

2017

Entrez Id: 27034
Gene Symbol: ACAD8
ACAD8
Malignant neoplasm of colon and/or rectum
0.080 Biomarker BEFREE Conversely, any situation that impairs the efficiency of the 1,25-(OH)(2)D(3)/VDR signaling system at the level of the gut mucosa, e.g. vitamin D insufficiency, may increase risk for the development of IBD and colorectal cancer. 21801808

2011

Entrez Id: 27034
Gene Symbol: ACAD8
ACAD8
Malignant neoplasm of colon and/or rectum
0.080 Biomarker BEFREE Carcinogenesis in IBD: potential targets for the prevention of colorectal cancer. 19404270

2009