Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23476
Gene Symbol: BRD4
BRD4
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.340 AlteredExpression BEFREE JMJD6 has been reported to be over-expressed in oral, breast, lung, and colon cancers and plays important roles in regulation of transcription through interactions with transcription regulator BRD4, histones, U2AF65, Luc7L3, and SRSF11. 29176719

2017
Entrez Id: 23476
Gene Symbol: BRD4
BRD4
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.340 Biomarker BEFREE We found that BRD4 is critical for colon cancer proliferation, and its knockdown led to differentiation effects in vivo. 26752646

2016
Entrez Id: 23476
Gene Symbol: BRD4
BRD4
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.340 Biomarker BEFREE We used gastric and colon cancer cell lines to study the synergistic effect of As4S4 in combination with BRD4 inhibitor JQ1, or with chemotherapy drug cisplatin and irinotecan or with COX2 inhibitor celecoxib. 26586936

2015
Entrez Id: 23476
Gene Symbol: BRD4
BRD4
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.340 Biomarker BEFREE Ectopic re-expression of BRD4 in these colon cancer cell lines markedly reduced in vivo tumor growth, suggesting a role of BRD4 in human colon cancer. 22120039

2012