Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8243
Gene Symbol: SMC1A
SMC1A
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 Biomarker BEFREE Collectively, the present results suggested that SMC1 served an important role in the development of CRC and may be a predictive prognostic biomarker in patients with CRC. 31524239

2019
Entrez Id: 8243
Gene Symbol: SMC1A
SMC1A
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 AlteredExpression BEFREE Here we showed that SMC1A cohesin core gene was present as extra-copies, mutated, and overexpressed in human colorectal carcinomas. 30823889

2019
Entrez Id: 8243
Gene Symbol: SMC1A
SMC1A
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 Biomarker BEFREE We investigated the particular effects as well as the underlying mechanism of SMC1A on TAFs recruitment during liver metastasis of colorectal cancer. 27826041

2017
Entrez Id: 8243
Gene Symbol: SMC1A
SMC1A
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 Biomarker BEFREE The findings of this study suggest that SMC1A plays an oncogenic role in colorectal cancer and that it might be a promising target for colorectal cancer therapy. 26637483

2016
Entrez Id: 8243
Gene Symbol: SMC1A
SMC1A
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 Biomarker BEFREE Stable SMC1A knockdown CRC cell lines were employed. 25884313

2015
Entrez Id: 8243
Gene Symbol: SMC1A
SMC1A
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 GeneticVariation BEFREE Our findings that SMC1A mutations decrease from early adenomas to colorectal cancers and that mutations lead to CIN suggest that mutant cohesin could play a pivotal role during colorectal cancer development. 25080505

2014
Entrez Id: 8243
Gene Symbol: SMC1A
SMC1A
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 GeneticVariation BEFREE SMC1A mutations have also been identified in colorectal cancers. 19842212

2010