Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
CUI: C0011847
Disease: Diabetes
Diabetes 		0.170 PosttranslationalModification BEFREE Additionally, silencing of ANRIL reduces myocardial injury in diabetes by inhibiting myocardial oxidative stress. 31211466

2019
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
CUI: C0011847
Disease: Diabetes
Diabetes 		0.170 Biomarker BEFREE Long noncoding RNA-antisense noncoding RNA in the INK4 locus accelerates wound healing in diabetes by promoting lymphangiogenesis via regulating miR-181a/Prox1 axis. 30565672

2019
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
CUI: C0011847
Disease: Diabetes
Diabetes 		0.170 Biomarker BEFREE However, it is currently not understood how CDKN2B-AS1 transcripts translate into diabetes. 30108282

2019
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
CUI: C0011847
Disease: Diabetes
Diabetes 		0.170 GeneticVariation BEFREE Our study concludes that ANRIL regulates functional and structural alterations in the kidneys and hearts in diabetes through controlling the expressions of ECM proteins and VEGF. 29118015

2018
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
CUI: C0011847
Disease: Diabetes
Diabetes 		0.170 Biomarker BEFREE Multiple logistic regression models indicated that drinking (odds ratio [OR]=2.09, 95% CI: 1.08-4.04, P=0.028), hypertension (OR=2.01, 95% CI: 1.14-3.57, P=0.017), diabetes (OR=3.15, 95% CI: 1.63-3.57, P<0.001), low-density lipoprotein (OR=3.14, 95% CI: 1.57-6.31, P=0.001), and ANRIL (OR=2.21, 95% CI: 1.68-2.92, P<0.001) were the independent risk factors for ISR. 28970468

2017
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
CUI: C0011847
Disease: Diabetes
Diabetes 		0.170 Biomarker BEFREE ANRIL knockout mice, with or without streptozotocin-induced diabetes, were also investigated. 28122089

2017
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
CUI: C0011847
Disease: Diabetes
Diabetes 		0.170 AlteredExpression BEFREE Our study demonstrates that CHD and periodontitis are genetically related by at least one susceptibility locus, which is possibly involved in ANRIL activity and independent of diabetes associated risk variants within this region. 19214202

2009