Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE Associations of DISH with the presence and extent of CAC were analyzed with and without adjustment for COPD and known atherosclerotic risk factors, including age, sex, race, diabetes, hypertension, high cholesterol, body mass index and smoking. 31181416

2019

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE Additional significant predictors for inpatient admission included history of bleeding disorder (OR 5.44, 95% CI 2.14-12.76), Asian race (OR 6.47, 95% CI 4.90-8.56), COPD (OR 3.10, 95% CI 1.94-4.82), diabetes (OR 1.90, 95% CI 1.43-2.49), and increased operation time (OR 3.01, 95% CI 2.69-3.37). 30807886

2019

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 GeneticVariation BEFREE Pooled prevalence for the most significant NCDs was a follows; cancer 8% (95% CI 6-10%), cardiovascular disease 38% (95% CI 33-42%), hypertension 39% (95% CI 32-47%), diabetes 14% (95% CI 12-16%), COPD prevalence estimates ranged from 4% to 18%.Heterogeneity across studies was high. 30590404

2019

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 GeneticVariation BEFREE On multivariate analysis the preoperative risk factors associated with CCC included ASA Class IV-V (OR:2.04, p < 0.0001), diabetes (OR = 1.28, p = 0.0001), pre-operative ventilator use (OR: 17.75, p = 0.0003); COPD (OR: 1.65, p < 0.0001); pre-operative weight loss >10% (OR: 1.35, p = 0.0026); pre-operative sepsis (OR: 2.14, p < 0.0001). 30528789

2019

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE Higher BDI scores were associated with a history of depression (p < 0.001), higher NYHA class (p < 0.001), diabetes (p < 0.001), COPD (p = 0.007), renal disease (p < 0.001) and stroke (p = 0.02). 30929707

2019

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE The results indicated that age standardized mortality rate for cancers, CVDs, and Asthma and COPD will continue to decrease in both sexes (cancers: from 81.8 in 2015 to 45.2 in 2030, CVDs: 307.3 to 173.0, and Asthma and COPD: from 52.1 to 46.6); however, in terms of diabetes, there is a steady trend in both sexes at national level (from 16.6 to 16.5). 30763320

2019

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE PRs for patients with diabetes and COPD were also evaluated. 30785928

2019

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE However, we failed to detect any statistically significant association between diabetes and COPD mortality. 31839642

2019

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE Female sex (P = 0.010), diabetes (P = 0.042), COPD (P = 0.011), and disseminated cancer (P = 0.032) trended toward morbidity in PLIF/TLIF; obesity trended in PLIF/TLIF (P = 0.0022) and ALIF/LLIF (P = 0.020). 30138253

2019

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE Significant predictors of mortality were diabetes (hazard ratio, HR [95% CI]: 2.41 [1.15-5.08]), chronic kidney disease (HR [95% CI]: 4.89 [1.97-12.13]), and COPD (HR [95% CI]: 3.31 [1.43-7.71]; all P values <.05). 30614413

2019

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE The glucagon-like peptide-1 receptor (GLP-1R) agonist - liraglutide (LIR) - is an insulin secretagogue for the treatment of diabetes and has been proven to have therapeutic potential in the treatment of COPD. 30349227

2019

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE In multivariate analysis, predictors of RI included asthma and COPD (OR 4.04, CI 1.82-8.96), hernia PC (OR 1.47, CI 1.48-1.98), EAV PC (OR 1.24, CI 1.04-1.48), increased age (OR 1.04, CI 1.01-1.06), and diabetes (OR 1.8, CI 1.11-2.91). 31637601

2019

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE Comorbidities like diabetes or COPD increase patients' susceptibility to infections, but it is unclear how the onset of comorbidity impacts antibiotic use. 31631225

2019

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 GeneticVariation BEFREE Comorbidities included the following: obesity (n = 95, 78.5%), hypertension (n = 72, 59.5%), cardiovascular disease (n = 42, 34.7%), diabetes (n = 40, 33.1%), COPD (n = 34, 28.1%), malignancy (n = 30, 24.8%), active smoker (n = 28, 23.1%), immunosuppression (n = 10, 8.3%), chronic corticosteroid use (n = 6, 5.0%), advanced age (n = 6, 5.0%), hypoalbuminemia (n = 3, 2.5%), and renal insufficiency (n = 1, 0.8%). 29063307

2018

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 GeneticVariation BEFREE Associations of non-cardiovascular comorbidities with patient-rated health were explained by their associations with shortness of breath (diabetes, OR 1.17, 95% CI 1.03 to 1.32; chronic kidney disease [CKD, OR 1.23, 95% CI 1.10 to 1.38; chronic obstructive pulmonary disease [COPD], OR 95% CI 1.84, 1.62 to 2.10) and with fatigue (diabetes, OR 1.27, 95% CI 1.13 to 1.42; CKD, OR 1.24, 95% CI 1.12 to 1.38; COPD, OR 1.69, 95% CI 1.50 to 1.91). 29584734

2018

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE The scoring system includes the following items: female gender (+2 points), age (50-69 years +7 points, 70-79 years +12 points, >80 years +15 points), diabetes (+4 points), COPD (+5 points), ischemic heart disease (+4 points), carotid stenosis> 90% (+4 points).Antiplatelet (-7 points).The score range from -7 to 26 points. 25073889

2017

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE They were more likely to be women, have diabetes and COPD, and less likely to have heart failure and had a lower mean CHADS<sub>2</sub> score (3.3 vs 3.5). 28645473

2017

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE We analyzed how diffusing capacity in patients with COPD is affected by the concurrent diagnosis of diabetes. 28086884

2017

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 GeneticVariation BEFREE We found higher prevalences of previous coronary artery disease (CAD) (38%), other atherosclerotic diseases (20.4%), cardiac risk factors such as hypertension (84.3%), diabetes (49.1%), hyperlipidemia (50.9%), heart failure (42.6%), atrial fibrillation (AF) (25.0%), severe aortic stenosis (13.0%), severe mitral regurgitation (3.7%), and implantable devices (25.0%), and co-morbidities such as renal impairment (48.1%), COPD (12.0%), and previous stroke (6.5%). 28320990

2017

Entrez Id: 260431
Gene Symbol: COPD
COPD
CUI: C0011847
Disease: Diabetes
Diabetes
0.100 Biomarker BEFREE In COPD, the probability of having diabetes (<i>P</i>=0.024) and gastroesophageal reflux (<i>P</i>=0.0048) at baseline increased in parallel with VAT accumulation, while the predicted MT attenuation increased the probability of cardiovascular comorbidities (<i>P</i>=0.042). 28203068

2017