Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9311
Gene Symbol: ASIC3
ASIC3
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.020 GeneticVariation BEFREE In the ANDnet, we furthermore identified potential glioma suppressor genes ACCN3 and ACCN4 linked to the NBPF1 neuroblastoma breakpoint family, as well as numerous ABC transporter genes (ABCA1, ABCB1) suggesting drug resistance of glioblastoma tumors. 28019039

2017
Entrez Id: 9311
Gene Symbol: ASIC3
ASIC3
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.020 Biomarker BEFREE Some of these currents had kinetics typical for ASICs and were sensitive to specific toxin inhibitors of ASIC1a or ASIC3, demonstrating that the GBM cell lines express functional ASIC1a and ASIC3 that may enable GBM cells to sensitively detect extracellular pH in a tumour tissue. 29057936

2017