Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0023418
Disease: leukemia
leukemia 		0.060 GeneticVariation BEFREE The interferon regulatory factor 1 (IRF-1) gene is located at 5q31, the site of common deletions in myelodysplastic syndromes (MDS) and secondary leukemias. 10807049

2000
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0023418
Disease: leukemia
leukemia 		0.060 Biomarker BEFREE The loss of functional IRF-1 has been observed in a number of patients with myelodysplastic syndrome (MDS) and leukemia, suggesting a potentially critical role of IRF-1 in leukemogenesis. 10609788

1999
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0023418
Disease: leukemia
leukemia 		0.060 Biomarker BEFREE The loss of functional IRF-1 has been observed in a significant number of patients with myelodysplastic syndrome (MDS) and leukemia, suggesting a potentially critical role of IRF-1 in human oncostasis. 9315094

1997
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0023418
Disease: leukemia
leukemia 		0.060 GeneticVariation BEFREE This result predicts diminished expression of PKR as a potential consequence of deletion of the IRF-1 gene in human leukemias. 8622878

1996
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0023418
Disease: leukemia
leukemia 		0.060 AlteredExpression BEFREE Accelerated exon skipping of IRF-1 mRNA in human myelodysplasia/leukemia; a possible mechanism of tumor suppressor inactivation. 7936656

1994
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0023418
Disease: leukemia
leukemia 		0.060 Biomarker BEFREE Thus, IRF-1 may be a critically deleted gene in human leukemia and myelodysplasia. 8438156

1993