Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker BEFREE High HLA-ABC and HLA-G were associated with tumor aggressiveness and could be relevant predictive markers for effective immunotherapy of melanoma tumors. 28882620

2017
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker BEFREE Examination of subcellular localization of wild-type ABCB6 in a B16 mouse melanoma cell line revealed that it is localized to the endosome-like compartment and dendrite tips, whereas disease-causing mutations of ABCB6 resulted in its retention in the Golgi apparatus. 23519333

2013
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker BEFREE Mithramycin A, an inhibitor of Sp1 binding, downregulated the expression of ABCB8 (and other ABC genes) in a concentration-dependent manner and sensitized a melanoma cell line to doxorubicin treatment. 21046154

2011