Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 369
Gene Symbol: ARAF
ARAF
CUI: C0025202
Disease: melanoma
melanoma
0.030 Biomarker BEFREE Vemurafenib, a RAF inhibitor, extends survival in patients with BRAF(V600)-mutant melanoma but activates extracellular signal-regulated kinase (ERK) signaling in RAS-mutant cells. 24589925

2014

Entrez Id: 369
Gene Symbol: ARAF
ARAF
CUI: C0025202
Disease: melanoma
melanoma
0.030 GeneticVariation BEFREE Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. 20823850

2010

Entrez Id: 369
Gene Symbol: ARAF
ARAF
CUI: C0025202
Disease: melanoma
melanoma
0.030 Biomarker BEFREE In a series of articles published in February 2010, The New York Times chronicled, from a personal perspective, the rollercoaster experience of those associated with clinical trials of a RAF inhibitor for the treatment of melanoma. 20538617

2010