Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.050 Biomarker BEFREE Since exosomes-derived epidermal growth factor receptor ligands (EGFR) are involved in tumor-associated osteolysis, we hypothesize that the EGFR ligand amphiregulin (AREG) can be delivered by MM-derived exosomes and participate in MM-induced osteoclastogenesis. 30621731

2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.050 Biomarker BEFREE In total, 98 patients were included in this retrospective translational research study and were evaluated for Kirsten rat sarcoma viral oncogene homolog (KRAS) mutational status, and v-akt murine thymoma viral oncogene homolog 1 (AKT1), AKT serine/threonine kinase 2 (AKT2), AKT serine/threonine kinase 3 (AKT3), cyclin D1 (CCND1), epidermal growth factor receptor (EGFR), mitogen-activated protein kinase 1 (MAPK1), hepatocellular growth factor receptor (MET), avian myelomatosis viral oncogene homolog (MYC), nuclear factor kappa B subunit 1 (NFKb1), phosphatase and tensin homolog (PTEN) and mechanistic target of rapamycin (FRAP1) genes mRNA expression. 27919956

2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.050 Biomarker BEFREE Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling. 27132469

2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.050 Biomarker BEFREE Our results contributed to the individualized targeted therapy with EGFR inhibitors in MM. 25894462

2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.050 AlteredExpression BEFREE Identification of a novel t(7;14) translocation in multiple myeloma resulting in overexpression of EGFR. 23765574

2013