Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0026985
Disease: Myelodysplasia
Myelodysplasia 		0.050 Biomarker BEFREE One allele of interferon regulatory factor-1 (IRF-1), a transcriptional activator of genes critical for growth suppression, differentiation, and apoptosis, is usually deleted in acute myeloid leukemias (AML) and myelodysplasias (MDS) with deletion of chromosome 5q31. 10602416

1999
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0026985
Disease: Myelodysplasia
Myelodysplasia 		0.050 GeneticVariation BEFREE Its overexpression results in inhibition of cell growth, and deletions of the IRF-1 gene were demonstrated in a number of human leukemias and myelodysplasias. 8622878

1996
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0026985
Disease: Myelodysplasia
Myelodysplasia 		0.050 AlteredExpression BEFREE Accelerated exon skipping of IRF-1 mRNA in human myelodysplasia/leukemia; a possible mechanism of tumor suppressor inactivation. 7936656

1994
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0026985
Disease: Myelodysplasia
Myelodysplasia 		0.050 Biomarker BEFREE Allelic loss of IRF1 in myelodysplasia and acute myeloid leukemia: retention of IRF1 on the 5q- chromosome in some patients with the 5q- syndrome. 8219215

1993
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0026985
Disease: Myelodysplasia
Myelodysplasia 		0.050 Biomarker BEFREE Thus, IRF-1 may be a critically deleted gene in human leukemia and myelodysplasia. 8438156

1993