Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.040 Biomarker BEFREE Finally, coexpression of CXCR4 and CXCR7 receptors significantly and selectively increased NB dissemination toward the bone marrow. 25955316

2015

Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.040 AlteredExpression BEFREE As determined by RT-PCR, CXCR7 expression was mainly detected in N-and S-type NB cell lines, and was slightly induced upon NB cell differentiation in vitro. 22916293

2012

Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.040 Biomarker BEFREE Neuroblastoma expressed both of the SDF-1 receptors CXCR4 and CXCR7. shRNA knockdown showed that these receptors were responsible for the migration of neuroblastoma towards MSCs. 21906874

2011

Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.040 AlteredExpression BEFREE In addition, RDC-1 is expressed in a unique subset of tumors of the peripheral nervous system including neuroepitheliomas and Ewing's sarcomas but not neuroblastomas. 1357630

1992