Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 799
Gene Symbol: CALCR
CALCR
CUI: C0029456
Disease: Osteoporosis
Osteoporosis
0.500 Biomarker BEFREE The calcitonin receptor (CTR) is a class B G protein-coupled receptor that is a therapeutic target for the treatment of hypercalcaemia of malignancy, Paget's disease and osteoporosis. 29277692

2018

Entrez Id: 799
Gene Symbol: CALCR
CALCR
CUI: C0029456
Disease: Osteoporosis
Osteoporosis
0.500 GeneticVariation BEFREE We suggest for the first time a protective role against osteoporosis in GD1 patients for the CC genotype of the c.9C>G gene variant in the TNFRSFB11 (OPG) gene and for the CC genotype of the c.1340T>C gene variant (CALCR gene), while the AA genotype of the c.1024+283G>A gene variant in the VDR gene appears as a risk factor for lower BMDs. 30498352

2018

Entrez Id: 799
Gene Symbol: CALCR
CALCR
CUI: C0029456
Disease: Osteoporosis
Osteoporosis
0.500 GeneticVariation BEFREE The C1377T polymorphism in the CTR gene is associated with BMD at the lumbar spine in a postmenopausal Han Chinese population and the CTR gene may become a useful genetic marker for predicting the risk of developing osteoporosis in postmenopausal Chinese women. 25055932

2015

Entrez Id: 799
Gene Symbol: CALCR
CALCR
CUI: C0029456
Disease: Osteoporosis
Osteoporosis
0.500 GeneticVariation BEFREE There is no consensus whether CTR gene polymorphism plays a role in affecting pathogenesis of osteoporosis. 24522475

2014

Entrez Id: 799
Gene Symbol: CALCR
CALCR
CUI: C0029456
Disease: Osteoporosis
Osteoporosis
0.500 Biomarker BEFREE In the combined genotype analysis, ER1/CALCR TCCC combined genotype was estimated to have protective effect against osteoporosis [p=0.0125, OR=0.323, 95% CI (0.1383-0.755)] whereas BGLAP/Col1A1 CCTT and ER1/CALCR CCTT combined genotypes were estimated as risk factors for osteoporosis in Turkish population (p=0.027, p=0.009 respectively). 23137636

2013

Entrez Id: 799
Gene Symbol: CALCR
CALCR
CUI: C0029456
Disease: Osteoporosis
Osteoporosis
0.500 GeneticVariation BEFREE Association analyses and multivariate two-step regression model of social and molecular parameters, demonstrated that in comparison to the VDR, ESR, CTR polymorphisms, physical activities and healthy diet, associated with outdoor work are the best favourable prognostic factors for osteoporosis. 19255718

2009

Entrez Id: 799
Gene Symbol: CALCR
CALCR
CUI: C0029456
Disease: Osteoporosis
Osteoporosis
0.500 GeneticVariation BEFREE Our aim was to evaluate the correlation of the ALUI calcitonin receptor gene polymorphism to bone mineral density and their relationship to osteoporosis. 12771454

2003

Entrez Id: 799
Gene Symbol: CALCR
CALCR
CUI: C0029456
Disease: Osteoporosis
Osteoporosis
0.500 GeneticVariation BEFREE In conclusion, the polymorphism of CTR gene but not VDR and COLIA1 is associated with osteoporosis incidence and the levels of alkaline phosphatase and estradiol. 12016463

2002

Entrez Id: 799
Gene Symbol: CALCR
CALCR
CUI: C0029456
Disease: Osteoporosis
Osteoporosis
0.500 AlteredExpression BEFREE Calcitonin receptor mRNA in mononuclear leucocytes from postmenopausal women: decrease during osteoporosis and link to bone markers with specific isoform involvement. 10865224

2000

Entrez Id: 799
Gene Symbol: CALCR
CALCR
CUI: C0029456
Disease: Osteoporosis
Osteoporosis
0.500 GeneticVariation BEFREE The effects of CT on the physiology of a variety of organ systems are discussed and the relationship between polymorphisms in the CTR gene and bone mineral density (BMD)/osteoporosis is examined. 11298188

2000