Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.040 Biomarker BEFREE Our findings highlight a novel protective role for NEAT1 in PD and suggest a previously unknown mechanism for the neuroprotective traits of widely used preventive therapeutics.-Simchovitz, A., Hanan, M., Niederhoffer, N., Madrer, N., Yayon, N., Bennett, E. R., Greenberg, D. S., Kadener, S., Soreq, H. NEAT1 is overexpressed in Parkinson's disease substantia nigra and confers drug-inducible neuroprotection from oxidative stress. 31311324

2019
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.040 AlteredExpression BEFREE Human neuroblastoma cell line SH-SY5Y was treated with 1-Methyl-4-phenylpyridinium (MPP<sup>+</sup>) to mimic PD model in vitro. qRT-PCR was employed to detect the expression of NEAT1, IL-1β, IL-6 and TNF-α. 31228597

2019
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.040 Biomarker BEFREE However, the role of NEAT1 and its potential mechanism in Parkinson's disease (PD) largely remain uncharacterized. 29287722

2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.040 Biomarker BEFREE Up-regulated NEAT1 was found in MPTP-induced PD mice. 29575151

2018