Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.340 GeneticVariation BEFREE Mitochondrial metabolism is inhibited by the HIF1α-MYC-PGC-1β axis in BRAF V600E thyroid cancer. 30768848

2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.340 AlteredExpression BEFREE Human thyroid cancer cell line follicular thyroid carcinoma (FTC) 133 was endowed with aggressiveness by HIF-1α or β-catenin overexpression. 27840971

2017
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.340 Biomarker BEFREE Combining adjuvant HIF1α inhibitor chemotherapy with surgery might be an effective therapeutic strategy for thyroid cancer that is refractory to conventional treatments. 25862859

2015
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.340 Biomarker BEFREE These data indicate that IGF-I stimulates VEGF synthesis in thyroid carcinomas in an Akt-dependent pathway via AP-1 and HIF-1 alpha and provide the framework for clinical use of small-molecule inhibitors, including geldanamycin analogs, to abrogate proangiogenic cascades in thyroid cancer. 14602779

2003