Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis 		0.030 Biomarker BEFREE Immunohistochemistry was performed for specific OS markers xCT and iNOS and brain inflammation markers TLR4, COX-2 and NF-κB in cortical tissue derived from patients with HME, FCD IIa, IIb and TSC. 30303592

2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis 		0.030 Biomarker BEFREE As previously reported for miR146a, overexpression of miR147b reduced the expression of the pro-inflammatory mediators IL-6 and COX-2 after IL-1β stimulation in both astrocyte and tuberous sclerosis complex cell cultures. miR146a and miR147b overexpression decreased proliferation of astrocytes and promoted neuronal differentiation of human neural stem cells. 29384235

2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0041341
Disease: Tuberous Sclerosis
Tuberous Sclerosis 		0.030 Biomarker BEFREE We recently reported that prostaglandin biosynthesis and cyclooxygenase-2 were deregulated in TSC and LAM. 25347447

2014