Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0162565
Disease: Acute intermittent porphyria
Acute intermittent porphyria 		0.030 GeneticVariation BEFREE Because HLA-DR*0405 expression fails to protect mice from AIP, the HLA-DRB1*0405 allele appears to be an important risk factor for AIP on the HLA-DRB1*0405/DQB1*0401 haplotype. 20303356

2010
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0162565
Disease: Acute intermittent porphyria
Acute intermittent porphyria 		0.030 GeneticVariation BEFREE Although the HLA DRB1*0405-DQB1*0401 haplotype and Fc receptor-like 3 polymorphisms have been associated with AIP, the role of other genetic factors is largely unknown. 18341485

2008
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0162565
Disease: Acute intermittent porphyria
Acute intermittent porphyria 		0.030 Biomarker BEFREE The two critical HLA regions for susceptibility to AIP are limited to the HLA-DRB1*0405-DQB1*0401 in the class II and the ABCF1 proximal to C3-2-11, telomeric of HLA-E, in the class I regions. 17119950

2007