Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 57508
Gene Symbol: INTS2
INTS2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.040 GeneticVariation BEFREE This neoplastic progression is also associated with mutations and/or amplification of c-H-ras, int-2, c-neu, c-myc and MDM2, MSI at 11q25 and 13q12-q13 and loss of heterozygosity at 17p. 10493942

1999
Entrez Id: 57508
Gene Symbol: INTS2
INTS2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.040 Biomarker BEFREE These results suggest that amplification of int-2 or neighboring genes on 11q may participate in tumor progression and metastasis in patients with esophageal squamous cancer. 9316622

1997
Entrez Id: 57508
Gene Symbol: INTS2
INTS2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.040 GeneticVariation BEFREE These findings suggest that LOH at D17S5 may be involved in the early stage of breast carcinoma development, while INT2 amplification and LOH at 11p, 16q, and 18q appear to be genetic alterations that occur with tumor progression. 7903963

1993
Entrez Id: 57508
Gene Symbol: INTS2
INTS2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.040 Biomarker BEFREE Our data suggest relationships between tumor progression and both incidence and size of Myc, Neu, and Int-2 gene amplification. 1849359

1991