Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 83932
Gene Symbol: SPRTN
SPRTN
CUI: C0231341
Disease: Premature aging syndrome
Premature aging syndrome 		0.030 Biomarker BEFREE Cells deficient in SPRTN protease exhibit DPC-induced replication stress and genome instability, manifesting as premature ageing and liver cancer. 31316063

2019
Entrez Id: 83932
Gene Symbol: SPRTN
SPRTN
CUI: C0231341
Disease: Premature aging syndrome
Premature aging syndrome 		0.030 GeneticVariation BEFREE Mutations in SPRTN cause premature ageing and liver cancer in humans and mice; thus, defective DPC repair has great clinical ramifications. 30170832

2018
Entrez Id: 83932
Gene Symbol: SPRTN
SPRTN
CUI: C0231341
Disease: Premature aging syndrome
Premature aging syndrome 		0.030 Biomarker BEFREE The results point to an unexpected function of SPRTN and bring insight to the mechanisms that link premature aging and cancer. 25352099

2014