Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.130 Biomarker BEFREE Disruption of prion protein-HOP engagement impairs glioblastoma growth and cognitive decline and improves overall survival. 25151961

2015
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.130 GeneticVariation BEFREE A patient with Creutzfeldt-Jakob disease (CJD) with prion protein (PrP) gene codon 180 mutation (CJD 180) experienced cognitive decline over the 1.5-year period before her death. 20409635

2010
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.130 GeneticVariation BEFREE Our findings provide evidence that variability of the PRNP gene at codon 129 might contribute to accelerating the rate of earlier cognitive decline in DS subjects. 12796830

2003