Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 60
Gene Symbol: ACTB
ACTB
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.120 Biomarker BEFREE In Alzheimer's disease (AD), rod-like cofilin aggregates (cofilin-actin rods) and thread-like inclusions containing phosphorylated microtubule-associated protein (pMAP) tau form in the brain (neuropil threads), and the extent of their presence correlates with cognitive decline and disease progression. 19828813

2009
Entrez Id: 60
Gene Symbol: ACTB
ACTB
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.120 AlteredExpression BEFREE In addition to confirming sweeping transcriptomal differences documented in previous studies of cognitive decline, we present new evidence for up-regulation of actin-related processes and down-regulation of translation, RNA processing and localization, and vesicle-mediated transport in individuals with cognitive decline. 17174450

2008