Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 158506
Gene Symbol: CBLL2
CBLL2
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.060 AlteredExpression BEFREE The E3 ubiquitin ligase NEDD4 is translationally upregulated and facilitates pancreatic cancer. 28423617

2017
Entrez Id: 158506
Gene Symbol: CBLL2
CBLL2
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.060 Biomarker BEFREE Negative correlation of ITCH E3 ubiquitin ligase and miRNA-106b dictates metastatic progression in pancreatic cancer. 26621835

2016
Entrez Id: 158506
Gene Symbol: CBLL2
CBLL2
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.060 AlteredExpression BEFREE Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition. 25348515

2015
Entrez Id: 158506
Gene Symbol: CBLL2
CBLL2
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.060 Biomarker BEFREE Carboxyl terminus of heat shock protein 70-interacting protein (CHIP) is an E3 ubiquitin ligase that is involved in protein quality control and mediates several tumor-related proteins in many cancers, but the function of CHIP in pancreatic cancer is not known. 24722501

2014
Entrez Id: 158506
Gene Symbol: CBLL2
CBLL2
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.060 AlteredExpression BEFREE After transfecting the pRC-U plasmid into human pancreatic cancer cells, KRAS expression levels were determined. 23288781

2013
Entrez Id: 158506
Gene Symbol: CBLL2
CBLL2
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		0.060 AlteredExpression BEFREE Increased expression of the E3-ubiquitin ligase receptor subunit betaTRCP1 relates to constitutive nuclear factor-kappaB activation and chemoresistance in pancreatic carcinoma cells. 15735017

2005