DisGeNET - a database of gene-disease associations

Source: BEFREE

Disease: Malignant Squamous Cell Neoplasm ×

Gene: DDR2 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	4921
Gene Symbol:	DDR2

DDR2

CUI:	C0751688
Disease:	Malignant Squamous Cell Neoplasm

Malignant Squamous Cell Neoplasm

0.030

AlteredExpression

BEFREE

Expression of DDR2 mRNA was analyzed in 54 lung SCC tissues by qRT-PCR.

24885564

2014

Entrez Id:	4921
Gene Symbol:	DDR2

DDR2

CUI:	C0751688
Disease:	Malignant Squamous Cell Neoplasm

Malignant Squamous Cell Neoplasm

0.030

GeneticVariation

BEFREE

Our results highlight potential RTK-driven adaptive-resistant mechanisms upon DDR2 targeting, and they suggest new, rationale cotargeting strategies for DDR2-mutant lung SCC.

25348954

2014

Entrez Id:	4921
Gene Symbol:	DDR2

DDR2

CUI:	C0751688
Disease:	Malignant Squamous Cell Neoplasm

Malignant Squamous Cell Neoplasm

0.030

Biomarker

BEFREE

This article summarizes the current state of knowledge of DDR2 biology and signaling in lung squamous cell cancer.

24828669

2014