Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
CUI: C1167791
Disease: Skin toxicity
Skin toxicity 		0.030 GeneticVariation BEFREE Some allelic variants of ABCG2 and ABCB1 are also associated with occurrence of skin toxicity during the treatment of breast cancer with anti-cancer drugs. 30181081

2018
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
CUI: C1167791
Disease: Skin toxicity
Skin toxicity 		0.030 GeneticVariation BEFREE A dominant model showed that there was no significant association between the ABCG2 C421A polymorphism and the risk of gefitinib-induced toxicity, while the ABCG2 G34A polymorphism might be associated with an increased risk of skin toxicity in gefitinib therapy (relative risk =1.54, 95% CI 1.08-2.21, <i>P</i>=0.02). 29440914

2018
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
CUI: C1167791
Disease: Skin toxicity
Skin toxicity 		0.030 GeneticVariation BEFREE Here we investigated associations between allelic variants of EGFR, ABCG2, and the transporter protein ABCB1 with diarrhea and skin toxicity in gefitinib-treated patients. 17148776

2006