Source: CLINVAR

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0025202
Disease: melanoma
melanoma 		0.500 CausalMutation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0025202
Disease: melanoma
melanoma 		0.500 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0025202
Disease: melanoma
melanoma 		0.500 GeneticVariation CLINVAR Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications. 19234609

2009
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0025202
Disease: melanoma
melanoma 		0.500 CausalMutation CLINVAR Genetic and epigenetic alterations of the APC gene in malignant melanoma. 15133491

2004
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0025202
Disease: melanoma
melanoma 		0.500 CausalMutation CLINVAR Mutational analysis of CTNNB1 identified somatic mutations in 1 primary melanoma and 1 melanoma metastasis from 2 different patients (5%). 12124804

2002
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0025202
Disease: melanoma
melanoma 		0.500 CausalMutation CLINVAR One out of 62 (1.6%) cell lines was found to carry a mutation, indicating that aberration of the Wnt-1/wingless pathway through activation of beta-catenin is a rare event, even in melanoma cell lines. 11930117

2002
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0025202
Disease: melanoma
melanoma 		0.500 CausalMutation CLINVAR Loss of membranous expression of beta-catenin is associated with tumor progression in cutaneous melanoma and rarely caused by exon 3 mutations. 11950921

2002
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0025202
Disease: melanoma
melanoma 		0.500 CausalMutation CLINVAR Cytoplasmic and nuclear accumulation of beta-catenin is rarely caused by CTNNB1 exon 3 mutations in cutaneous malignant melanoma. 11351304

2001
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0025202
Disease: melanoma
melanoma 		0.500 CausalMutation CLINVAR Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma. 10027390

1999
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0025202
Disease: melanoma
melanoma 		0.500 CausalMutation CLINVAR Stabilization of beta-catenin by genetic defects in melanoma cell lines. 9065403

1997