Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3084
Gene Symbol: NRG1
NRG1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.500 Biomarker PSYGENET The neuregulin-1 (NRG1) gene is one of the best-validated risk genes for schizophrenia, and psychotic and bipolar disorders. 24865593

2014
Entrez Id: 3084
Gene Symbol: NRG1
NRG1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.500 Biomarker PSYGENET Neuregulin 1 (NRG1) is a bipolar disorder susceptibility gene and a biomarker of major depressive disorder, which regulates pyramidal neuron activity via ErbB4 in parvalbumin interneurons. 24633675

2014
Entrez Id: 3084
Gene Symbol: NRG1
NRG1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.500 Biomarker PSYGENET Based on the function of neuregulin 1 (NRG1) in neurodevelopment, susceptibility to bipolar disorder presumably involves this gene. 24767010

2014
Entrez Id: 3084
Gene Symbol: NRG1
NRG1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.500 Biomarker PSYGENET In this study we investigated 36 single nucleotide polymorphisms within 10 genes previously associated with major depression and bipolar disorder, as well as with the response to their treatment (ABCB1, ABCB4, TAP2, CLOCK, CPLX1, CPLX2, SYN2, NRG1, 5HTR1A and GPRIN2). 23273899

2013
Entrez Id: 3084
Gene Symbol: NRG1
NRG1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.500 Biomarker PSYGENET Neuregulin 1 (NRG1) is a frequently identified schizophrenia susceptibility gene that has also been associated with the psychotic features of bipolar disorder. 23022220

2013