Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7054
Gene Symbol: TH
TH
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.400 Biomarker PSYGENET Dopamine D4 receptor and tyrosine hydroxylase genes in bipolar disorder: evidence for a role of DRD4. 12232779

2002
Entrez Id: 7054
Gene Symbol: TH
TH
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.400 Biomarker PSYGENET Given a presumed role for norepinephrine (NE) in bipolar disorder, as well as the actions of mood-stabilizing drugs, we examined changes in mRNA expression for tyrosine hydroxylase (TH), the NE transporter (NET) and alpha 2A autoreceptor in the rat locus coeruleus after valproate treatment. 10633488

2000
Entrez Id: 7054
Gene Symbol: TH
TH
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.400 Biomarker PSYGENET We attempted to test the hypothesis that there was allelic association between polymorphisms around the tyrosine hydroxylase locus and bipolar affective disorder. 10616951

1999
Entrez Id: 7054
Gene Symbol: TH
TH
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.400 Biomarker PSYGENET The results of this association study do not confirm the possible implication of TH polymorphism in the susceptibility to BPAD. 10490711

1999
Entrez Id: 7054
Gene Symbol: TH
TH
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.400 Biomarker PSYGENET While positive associations between TH and bipolar affective disorder have been found in several studies, many studies have failed to reproduce these results. 10050974

1999