×
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
Malignant neoplasm of urinary bladder
0.800
Biomarker
CTD_human
Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation.
24121792 2013
×
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
Malignant neoplasm of urinary bladder
0.800
Biomarker
CTD_human
On the basis of its in vitro profile, compound 1h (NVP-BGJ398) was selected for in vivo evaluation and showed significant antitumor activity in RT112 bladder cancer xenografts models overexpressing wild-type FGFR3 .
21936542 2011
×
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
Malignant neoplasm of urinary bladder
0.800
Biomarker
CTD_human
Our results show a link between germline variants, somatic mutations of FGFR3 and risk of UBC .
20348956 2010
×
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
Malignant neoplasm of urinary bladder
0.800
Biomarker
CTD_human
Massively parallel sequencing of sperm DNA showed that levels of the FGFR3 mutation increase with paternal age and that the mutation spectrum at the Lys650 codon is similar to that observed in bladder cancer .
19855393 2009
×
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
Malignant neoplasm of urinary bladder
0.800
GeneticVariation
UNIPROT
Loss of heterozygosity at 4p16.3 and mutation of FGFR3 in transitional cell carcinoma.
11314002 2001
×
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
Malignant neoplasm of urinary bladder
0.800
GeneticVariation
UNIPROT
Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas.
10471491 1999
×
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
Malignant neoplasm of urinary bladder
0.800
CausalMutation
CGI
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of urinary bladder
0.700
Biomarker
CTD_human
Analysis of the relationship between pesticide exposure and mutation in the K-ras gene in human bladder cancer .
29644616 2018
×
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
Malignant neoplasm of urinary bladder
0.700
Biomarker
CTD_human
High susceptibility of human c-Ha-ras proto-oncogene transgenic rats to carcinogenesis: a cancer-prone animal model.
15958052 2005
×
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
Malignant neoplasm of urinary bladder
0.700
Biomarker
CTD_human
Activating missense mutations in Ha-ras-1 genes in a malignant subset of bladder lesions induced by N-butyl-N-(4-hydroxybutyl)nitrosamine or N-[4-(5-nitro-2-furanyl)-2-thiazolyl]formamide.
2278634 1990
×
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
Malignant neoplasm of urinary bladder
0.700
Biomarker
CTD_human
Oncogene expression of FANFT- or BBN-induced rat urothelial cells.
2228319 1990
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of urinary bladder
0.700
GeneticVariation
UNIPROT
×
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
Malignant neoplasm of urinary bladder
0.700
CausalMutation
CGI
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Malignant neoplasm of urinary bladder
0.690
Biomarker
CTD_human
Consistent with the aggressive clinical behavior of plasmacytoid carcinomas, which frequently recur locally, CRISPR/Cas9-mediated knockout of CDH1 in bladder cancer cells enhanced cell migration.
26901067 2016
×
Entrez Id: 472
Gene Symbol: ATM
ATM
Malignant neoplasm of urinary bladder
0.690
Biomarker
CTD_human
Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy.
24121791 2013
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Malignant neoplasm of urinary bladder
0.690
Biomarker
CTD_human
Promoter methylation as a common mechanism for inactivating E-cadherin in human salivary gland adenoid cystic carcinoma.
17520682 2007
×
Entrez Id: 472
Gene Symbol: ATM
ATM
Malignant neoplasm of urinary bladder
0.690
CausalMutation
CGI
×
Entrez Id: 472
Gene Symbol: ATM
ATM
Malignant neoplasm of urinary bladder
0.690
GenomicAlterations
CGI
×
Entrez Id: 5925
Gene Symbol: RB1
RB1
Malignant neoplasm of urinary bladder
0.610
GenomicAlterations
CGI
×
Entrez Id: 5925
Gene Symbol: RB1
RB1
Malignant neoplasm of urinary bladder
0.610
CausalMutation
CGI
×
Entrez Id: 5925
Gene Symbol: RB1
RB1
Malignant neoplasm of urinary bladder
0.610
Biomarker
CTD_human
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of urinary bladder
0.600
Biomarker
CTD_human
Genetic aberrations of the K-ras proto-oncogene in bladder cancer in relation to pesticide exposure.
29644616 2018
×
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
Malignant neoplasm of urinary bladder
0.600
Biomarker
CTD_human
Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors.
27111033 2016
×
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
Malignant neoplasm of urinary bladder
0.600
Biomarker
CTD_human
Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy.
24121791 2013
×
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
Malignant neoplasm of urinary bladder
0.600
Biomarker
CTD_human
A case-control study of polymorphisms in xenobiotic and arsenic metabolism genes and arsenic-related bladder cancer in New Hampshire.
22306368 2012