×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
PSYGENET
One functional single nucleotide polymorphism in dopamine receptor D2 (DRD2 ), rs1076560, is involved in regulating splicing of the gene and alters the ratio of DRD2 isoforms located pre- and postsynaptically. rs1076560 has been previously associated with cocaine abuse and we set out to confirm this association in a sample of European American (EA) (n = 336) and African American (AA) (n = 1034) cocaine addicts and EA (n = 656) and AA (n = 668) controls.
24359476 2014
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
PSYGENET
Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse : a gene-gene-environment interaction.
23340505 2013
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
PSYGENET
ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse .
23635803 2013
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
PSYGENET
To assess the role of DRD2 variants in cocaine abuse , we measured levels of D2S and D2L mRNA in human brain autopsy tissues (prefrontal cortex and putamen) obtained from cocaine abusers and controls, and genotyped a panel of DRD2 SNPs (119 abusers and 95 controls).
21150907 2011
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
CTD_human
Dopamine D3 and D2 receptor mechanisms in the abuse-related behavioral effects of cocaine: studies with preferential antagonists in squirrel monkeys.
20494958 2010
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Therapeutic
CTD_human
Dopamine D3 and D2 receptor mechanisms in the abuse-related behavioral effects of cocaine: studies with preferential antagonists in squirrel monkeys.
20494958 2010
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Therapeutic
CTD_human
D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats.
18418874 2008
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
CTD_human
D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats.
18418874 2008
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Therapeutic
CTD_human
Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration.
16541082 2007
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
CTD_human
Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement.
17332411 2007
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
CTD_human
Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration.
16541082 2007
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Therapeutic
CTD_human
Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement.
17332411 2007
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Therapeutic
CTD_human
Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving.
16971900 2006
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
CTD_human
Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving.
16971900 2006
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
CTD_human
Cocaine dependence and d2 receptor availability in the functional subdivisions of the striatum: relationship with cocaine-seeking behavior.
15010698 2004
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
CTD_human
Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats.
15042275 2004
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Therapeutic
CTD_human
Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats.
15042275 2004
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Therapeutic
CTD_human
Cocaine dependence and d2 receptor availability in the functional subdivisions of the striatum: relationship with cocaine-seeking behavior.
15010698 2004
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Therapeutic
CTD_human
Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists.
11923462 2002
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Therapeutic
CTD_human
Relapse to cocaine- and heroin-seeking behavior mediated by dopamine D2 receptors is time-dependent and associated with behavioral sensitization.
11751029 2002
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
CTD_human
Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists.
11923462 2002
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
CTD_human
Relapse to cocaine- and heroin-seeking behavior mediated by dopamine D2 receptors is time-dependent and associated with behavioral sensitization.
11751029 2002
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
CTD_human
Dopamine D1- and D2-like receptor mechanisms in relapse to cocaine-seeking behavior: effects of selective antagonists and agonists.
10900248 2000
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Therapeutic
CTD_human
Dopamine D1- and D2-like receptor mechanisms in relapse to cocaine-seeking behavior: effects of selective antagonists and agonists.
10900248 2000