Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Therapeutic CTD_human MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212. 20711185

2010
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Therapeutic CTD_human Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine. 20810894

2010
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker CTD_human Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaine. 20810894

2010
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker CTD_human MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212. 20711185

2010
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Therapeutic CTD_human A single intra-PFC infusion of BDNF prevents cocaine-induced alterations in extracellular glutamate within the nucleus accumbens. 19321768

2009
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker CTD_human A single intra-PFC infusion of BDNF prevents cocaine-induced alterations in extracellular glutamate within the nucleus accumbens. 19321768

2009
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker CTD_human Relapse to cocaine seeking increases activity-regulated gene expression differentially in the prefrontal cortex of abstinent rats. 18311559

2008
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Therapeutic CTD_human Relapse to cocaine seeking increases activity-regulated gene expression differentially in the prefrontal cortex of abstinent rats. 18311559

2008
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker CTD_human Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse. 17618281

2007
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Therapeutic CTD_human A BDNF infusion into the medial prefrontal cortex suppresses cocaine seeking in rats. 17651427

2007
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker CTD_human A BDNF infusion into the medial prefrontal cortex suppresses cocaine seeking in rats. 17651427

2007
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Therapeutic CTD_human Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse. 17618281

2007
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker CTD_human A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal. 14973246

2004
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Therapeutic CTD_human A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal. 14973246

2004