Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2847
Gene Symbol: MCHR1
MCHR1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.330 Biomarker PSYGENET The data indicate that MCH1R participates in the modulation of depression-like behavior through a process that involves the CA1 region of the hippocampus, supporting the possible use of MCH1R antagonists in the treatment of depression. 22209364

2012
Entrez Id: 2847
Gene Symbol: MCHR1
MCHR1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.330 Biomarker PSYGENET Preclinical evaluation of melanin-concentrating hormone receptor 1 antagonism for the treatment of obesity and depression. 19182070

2009
Entrez Id: 2847
Gene Symbol: MCHR1
MCHR1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.330 Biomarker PSYGENET Taken together, we suggest that antagonism of the MCHR1 receptor may provide a novel approach for the treatment of affective disorders, including depression, with a potentially increased efficacy in women. 16934771

2007
Entrez Id: 2847
Gene Symbol: MCHR1
MCHR1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.330 Biomarker PSYGENET MCHR1 antagonists might find an additional usage in the treatment of anxiety and depression disorders. 17655875

2007
Entrez Id: 2847
Gene Symbol: MCHR1
MCHR1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.330 Biomarker PSYGENET Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression. 16230605

2005