Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.520 Biomarker PSYGENET Recently it was demonstrated that GSK3? through a ?-arrestin2/protein kinase B (PKB or Akt)/protein phosphatase 2A (PP2A) signaling complex regulates dopamine (DA)- and lithium-sensitive behaviors and is required to mediate endophenotypes of mania and depression in rodents. 23188793

2013

Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.520 Biomarker PSYGENET In ED-treated mice, 4 weeks after METH treatment, we evaluated fear conditioning, depression-like responses in forced swim test, and the basal and METH-induced activity of AKT and GSK-3? in the ventral striatum. 21315744

2012

Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.520 Biomarker CTD_human A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors. 20534517

2010

Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.520 Biomarker CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757

2010

Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.520 Biomarker PSYGENET Response to lithium augmentation in depression is associated with the glycogen synthase kinase 3-beta -50T/C single nucleotide polymorphism. 17628506

2008