Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3620
Gene Symbol: IDO1
IDO1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.400 Biomarker PSYGENET These data indicate that activation of brain IDO1 is sufficient to induce depression-like behaviors of mice in response to central LPS. 23866724

2013
Entrez Id: 3620
Gene Symbol: IDO1
IDO1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.400 Biomarker PSYGENET IDO expression is driven by inflammatory cytokines, and has been suggested as the link between inflammation and a serotonergic deficit in depression. 22683764

2012
Entrez Id: 3620
Gene Symbol: IDO1
IDO1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.400 Biomarker PSYGENET These results reveal an IDO1-mediated regulatory mechanism underlying the comorbidity of pain and depression and suggest a new strategy for the concurrent treatment of both conditions via modulation of brain IDO1 activity. 22751107

2012
Entrez Id: 3620
Gene Symbol: IDO1
IDO1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.400 Biomarker PSYGENET Although the indoleamine 2,3-dioxygenase (IDO) enzyme seems to be involved in the pathophysiology of IFN-α-induced depression, no pharmacogenetic study has investigated whether variation in the IDO gene modifies vulnerability to this adverse effect. 21693183

2011