DisGeNET - a database of gene-disease associations

Source: CURATED

Disease: Heart failure ×

Gene: NFE2L2 ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	4780
Gene Symbol:	NFE2L2

NFE2L2

CUI:	C0018801
Disease:	Heart failure

Heart failure

0.370

Therapeutic

CTD_human

In addition, Nrf2 KO mice show biomarkers of heart failure, such as elevated levels of β-MHC, ANF, and BNP mRNA in the myocardium.

2017