Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0036572
Disease: Seizures
Seizures
0.400 Therapeutic CTD_human The seizures occurred following the suppression of infantile spasms with adrenocorticotropic hormone therapy and disappeared following the cessation of clonazepam administration. 1656808

1991

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0036572
Disease: Seizures
Seizures
0.400 Biomarker CTD_human The seizures occurred following the suppression of infantile spasms with adrenocorticotropic hormone therapy and disappeared following the cessation of clonazepam administration. 1656808

1991

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0036572
Disease: Seizures
Seizures
0.400 Biomarker CTD_human The features of these are 1) late onset of seizures, 2) good response to ACTH therapy, 3) no significant abnormalities of brain except for agenesis of corpus callosum. 2169275

1990

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0036572
Disease: Seizures
Seizures
0.400 Therapeutic CTD_human The features of these are 1) late onset of seizures, 2) good response to ACTH therapy, 3) no significant abnormalities of brain except for agenesis of corpus callosum. 2169275

1990

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0036572
Disease: Seizures
Seizures
0.400 Therapeutic CTD_human Therefore, we considered that the new brief tonic seizures, which appeared only during sleep in the course of ACTH therapy, were ACTH-induced seizures. 2554740

1989

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0036572
Disease: Seizures
Seizures
0.400 Biomarker CTD_human Therefore, we considered that the new brief tonic seizures, which appeared only during sleep in the course of ACTH therapy, were ACTH-induced seizures. 2554740

1989

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0036572
Disease: Seizures
Seizures
0.400 Biomarker CTD_human Cardiac hypertrophy associated with ACTH therapy for childhood seizure disorder. 2821097

1987

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0036572
Disease: Seizures
Seizures
0.400 Therapeutic CTD_human Cardiac hypertrophy associated with ACTH therapy for childhood seizure disorder. 2821097

1987

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0036572
Disease: Seizures
Seizures
0.400 Biomarker CTD_human [Modalities and side effects of ACTH therapy of diffuse epilepsy in children]. 6324019

1984

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0036572
Disease: Seizures
Seizures
0.400 Therapeutic CTD_human [Modalities and side effects of ACTH therapy of diffuse epilepsy in children]. 6324019

1984

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0036572
Disease: Seizures
Seizures
0.400 Therapeutic CTD_human Lower doses of systemic morphine (50 mg/kg) were necessary to block i.c.v. morphine seizures than the dose (100 mg/kg) necessary to block seizures induced by i.c.v.Leu-enkephalin and beta-endorphin. 7127082

1982

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0036572
Disease: Seizures
Seizures
0.400 Biomarker CTD_human Lower doses of systemic morphine (50 mg/kg) were necessary to block i.c.v. morphine seizures than the dose (100 mg/kg) necessary to block seizures induced by i.c.v.Leu-enkephalin and beta-endorphin. 7127082

1982